Yes, it's possible on Mac. I'm running it on my M1 laptop with no issues. You have to find where runelite is located and go inside the application by checking the Runelite application (Package info, I think) and add the osbot client in the resources folder (replace with the normal runelite client) then patch it with that file location.
Were you botting 24/7? Doesn't matter how good the script is, if you continously bot without doing other activities you will get ban. If your mouse patterns don't change, the detection system will pick up on that will slam you with the ban hammer.