try browsing the registry (Start > Run > regedit > OK) to the following value:  
Code: 
HKEY_LOCAL_MACHINE\Software\Classes\Installer\Products\<ProductSQUID>\ 
Where 'ProductSQUID' is the ID of the game (you'll have to go through the whole list of values, a daunting task) and check if there's a 'transform' entry on the registry key you believe to be created by the installer. Check if this entry is pointing to a valid Windows installation drive (where Windows is installed, most often the C: drive), and if not, change it. 
There's various programs that can possibly cut the work short but I'm not familiar with any and I'd leave it to you to do your research, hope this helped!