No, from my experience MAC has nothing to do with bans or HWID, only proxies matter. The point of proxy that jagex see's your bot connect though proxy named IP1, if you have more accounts on IP1 they check them too and then they ban all bots on IP1 simultaniously. But if you have accounts on IP2 even if they are bots if they are caught they won't get banned because of bans on IP1