One tip I feel strongly about is that if you plan on botting, get multiple bots and switch them around so that you aren't just building one skill or in one area for long periods. For instance, if you had the Czar rock crabs, giant spiders and ankou, you could use all of them in the period of a day with the confidence that Czar clients have come to know. You might throw some agility mage or herblore into the mix...
I don't know if any of the above makes any difference, but I have done a lot of botting, and even in RS2 I did, but I always had lots of them to mix up the day with. I probably bot about 1/3 to 1/2 of the time. I have never been banned or warned.