I'm just wondering if anyone has gotten banned from having bots (on a different ip) run rune essence to their main account (which wont be botted). So my question is can my main get banned for interacting with bots that run rune essence to it. 

if i remember right a youtuber got his main banned for setup some bots for fun for a video, never bot on his main but still banned

tho you never know if he can make a script to do what he did who say he cant have been botting his main as well lol.

Yes, if jagex decide your main is connected to the bots (which is pretty obvious if they are all running ess to you) you can get banned 

I would say it's unlikely and the price of essence is cheap as shit to begin with. I personally wouldn't take the risk or I would drop trade it over. Though, it's unlikely to get caught is it really worth the risk? I'm assuming they would check all logs of; trading and dueling. 

Could probably happen, just get a new acc and do it on that