How effective would this be?

[Helen Keller]

Probably not worth the effort

[Styx]

I would just write a method that deviates from the path by a couple of tiles so that you don't have to have a bunch of predetermined paths.  Perhaps even switch it up by having 70%-80% of clicks be on the minimap and having 20%-30% of the tiles being clicked directly (if you're worried about being detected).