It can also induce stress/anxiety since the effects are different from strain to strain and person to person as well as the does you take and if you smoke it or use edibles.
For example, I prefer edibles but smoke it most of the time because it's cheaper, and I smoke on a few puffs for the reaxing body effects like pain relief because I have extreme back and leg muscle pain. I don’t smoke more than that because I don’t use it for the cerebral effects nor do I care to.
Also as the post above, adding nicotine into the mix with tabacco leaf as the paper will change the effects more since you add another variable/high. Just like mixing weed and alcohol together will add the effects of both.